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Between the s and the s, there was a significant increase in livestock production, both by numbers and by carcass weight, especially among beef, pigs and chickens, the latter of which had production increased by almost a factor of Of course, the amount of weight you use is important for achieving maximum intensity; and you want to use the principle of progressive overload, and gradually use and progress to the heaviest weights possible. Eisenhauer L Nov 7, About second reference osteoporosis Chriss describe this so I dont think need do the same read his reference and then you will see flaws in study provided by you. The gym have no more weights to put on.. Network with the best of the best. I will have to get some more plates soon.

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Advice on practical solutions to technical challenges and unmet needs that are encountered in the laboratory practice. A place to share information on topics such as advice, experience, and resources for mentoring, training, teaching, having visitors in your laboratory, and contact with others in the field. This section will include contributions from forward-thinking individuals in the field who wish to share their vision, intuitions, experience, and perceptions with JALM readers and the laboratory medicine field.

Submissions to Laboratory Reflections are limited to words and should not include an abstract. The references are limited to 5, and only 1 table or figure is permitted. Supplemental data are not permitted. This section celebrates the important moments and individuals note-worthy to the field of clinical chemistry.

Letters are submitted directly from authors and can be used to report an observation or to discuss a previously published original Article.

Letters in response to papers other than Articles or Case Reports will not be considered for publication. Letters report observations on interferences, suggestions to improve test performance, or other observations that are of importance to the wider audience. A Reply to a Letter may also be solicited by the editors.

The one figure or table provided should be concise and should not be multipart i. A Letter to the Editor is limited to words. It should not include an abstract. Supplemental data are not permitted for Letters to the Editor. A Reply is limited to words. Supplemental data are not permitted for Replies. Letters to the Editor and Replies should list no more than 8 authors, with any additional contributors listed in the Acknowledgments.

In some instances, editors may request that a submission of another article type to JALM be decreased to meet the requirements of a Letter to the Editor. Mini-Reviews may be submitted directly by authors or invited by the journal. Mini-Reviews are intended to provide a general overview of a topic.

Basic information is provided, along with selected references that can aid the reader in obtaining additional information about the subject. The use of illustrative figures or tables is encouraged. A Mini-Review article should consist of a structured abstract limited to words with headings of Background, Content, and Summary. The text should not exceed 3, words. Mini-Reviews should list no more than 5 authors, with any additional contributors listed in the Acknowledgments. They present the belief or personal view of the author s on a specific topic.

Unlike Editorials and Letters to the Editor, Opinion articles do not comment on, or refer to, specific papers published in this or any other journal. An Opinion should not include an abstract and is limited to 1, words, 15 references, 1 table or figure, and no more than 5 authors.

Supplemental data are not permitted for Opinions. These articles are typically invited submissions from experts in a selected discipline and provide different viewpoints on a topic that may be controversial, lacks consensus in the scientific community, or may be of high public interest.

The manuscript is limited to 1, words, 15 references, and 1 table or figure. Reviews are intended to provide comprehensive coverage of a topic, including background clinical or analytical information, the relevance and importance of the subject matter, and potential future directions. A Review article should consist of a structured abstract with headings of Background, Content, and Summary limited to words. The text should not exceed 5, words. Exceptions to the reference count may be made at the discretion of the editor.

Supplemental data are encouraged for Review articles. Reviews should list no more than 15 authors, with any additional contributors listed in the Acknowledgments. Special Reports may be submitted directly by authors or invited by the journal. The types of papers that would be considered include consensus reports, guideline development, position statements, or evidence-based recommendations on test utilization or quality specifications.

The editors may also decide to classify other miscellaneous submissions under this heading. A Special Report should consist of a structured or unstructured abstract limited to words. The main text should be no more than 5, words. Supplemental data are permitted for Special Reports. Special Reports should list no more than 20 authors, with any additional contributors listed in the Acknowledgments.

For more information or to request open access publication, contact the Editorial Office at jalm aacc. All papers are made open access one year after publication. Articles are grouped in the journal according to subject. Upon submission, authors are required to select the journal category that best describes their manuscript from the list indicated below:.

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All pages must be double-spaced and all lines numbered. The body of the paper should include: Introduction, Materials and Methods, Results and Discussion. Full corporate names of manufacturers of materials should be utilized omit Inc.

After the first mention, use a shorter name e. Reporting of Concentration Units: Use of human subjects requires a statement in the text indicating whether the procedures followed were approved by your institution's responsible committee Institutional Review Board or Ethics Committee or were in accordance with the current revision of the Helsinki Declaration and whether subjects gave informed consent.

Accession numbers for data sets or sequence reads that have been deposited in a public database should be provided in the Materials and Methods section of the text. Where applicable, a ClinicalTrials. If you include research funding in the Acknowledgment, you must specify which author or authors received the funding or if the funding was given to the group or institution. Editorial staff will transfer this information to the disclosure section prior to publication if the paper is accepted.

References should appear in a separate section directly following the body of the manuscript. In-text citations should correspond to the numbered references in this list and should be formatted as follows: Abstract and supplement numbers should be provided, if applicable.

Personal communications should also be listed parenthetically and should contain the first initial and last name of the contact as well as the month and year of the communication. A copy of written permission from the contact to use the communication must also be provided. Published manuscripts and manuscripts that have been accepted and are pending publication should be cited in the reference list. Note that unpublished material must be published, at least online, by the time of publication of the citing article.

In-press references cited in the reference list must be accompanied by a copy of the cited manuscript and a letter of acceptance, or a complete author proof from the publisher. These resources should be uploaded as supplemental data along with the manuscript and other print materials. The submission system will extract the references from the submitted MS Word document. This linking option allows for the checking of the correct formatting and the accuracy of the citations. Correct linking of the references depends on strict adherence to Journal style as indicated.

JALM style is available in the Endnote reference formatting program. In particular, journal names may not be abbreviated correctly in the output. If you have used PubMed for journal name abbreviations, it is recommended that you take the following steps:.

Refer to the Endnote Help Center for further assistance. A case of pseudoparaproteinemia on capillary zone electrophoresis caused by geloplasma. Affinity binding assay of glycohemoglobin by two-dimensional centrifugation referenced to hemoglobin Alc. Quantification of rhesus monkey albumin with assays for human microalbumin [Abstract].

New biochemical marker for bone disease: Davey L, Naidoo L. Urinary screen for acetaminophen paracetamol in the presence of N-acetylcysteine [Letter]. Rifai N, Warnick GR. Lipids, lipoproteins, apolipoproteins, and other cardiovascular risk factors.

Tietz textbook of clinical chemistry and molecular diagnostics. Immunonephelometric measurement of vitamin D binding protein [MAppSci thesis]. University of Technology, PCR-based methods for the enrichment of minority alleles and mutations. Lipids, risk factors and ischaemic heart disease.

American Association for Clinical Chemistry. Tables are considered text. They should appear embedded as part of the submission directly following the reference section. Each table should appear on an individual page.

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Submissions will be returned to authors if the figures are embedded within the manuscript file and not uploaded separately or if the figures have become illegible in the merged PDF.

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Authors of a manuscript rejected by Clinical Chemistry will receive a decision email with detailed instructions on how to transfer their paper to JALM. Should the author choose to do so, they may revise their manuscript addressing any Clinical Chemistry reviewer comments and transfer their paper and blinded reviews if there are any to JALM as detailed in the instructions provided in the email. Authors will have 30 days to complete the transfer before the portal closes for each manuscript. Authors will have the opportunity, and are encouraged, to edit any part of the submission disclosures, contributions, author list, abstract, etc.

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Document the analytical advantages of the new or modified method over existing methods. Standard deviations of repeated points may be included. For acceptable alternatives that include only one run per day, see the cited document. Bioanalytical Method Evaluation, Linnet K, Boyd JC.

Selection and analytical evaluation of methods — with statistical techniques. User evaluation of precision performance of clinical chemistry devices. Theory, practice and correlation, 2nd ed. Selection and evaluation of methods. Tietz textbook of clinical chemistry, 2nd ed. Necessary sample size for method comparison studies based on regression analysis.

Evaluation of regression procedures for methods comparison studies. General Deming regression for estimating systematic bias and its confidence interval in method-comparison studies. Executable program for general Deming regression calculations and graphics.

Statistical methods for assessing agreement between two methods of clinical measurement. Commentary on quantifying agreement between two methods of measurement. Partly nonparametric approach for determining the limit of detection. Analytical performance characteristics should be judged against objective quality specifications. Establishment and use of reference values. Tietz textbook of clinical chemistry, 4th ed. Ion Suppression in Mass Spectrometry.

Statistics Describe statistical methods with enough detail to enable a knowledgeable reader with access to the original data to verify the reported results. On P values and confidence intervals why can't we P with more confidence? Checklist for the Description of Sequence Variants at the Human Genome Variation Society Requirements for the description of sequence variants can be found at http: Specify spectrum of evaluated patients age and sex distributions, eligibility criteria, and summary of symptoms or disease stage.

Analyze pertinent subgroups of subjects e. Avoid verification bias usually by application of a "gold-standard" test to all subjects rather than to a clinically selected subset. Categorize test results and patients independently to avoid reviewer bias usually by performance of tests with blinding to patient information and vice versa.

Indicate the number of indeterminate test results and their use if any in further data analysis. Provide laboratory data on analytical imprecision of the test usually day-to-day CV at two or more concentrations or reproducibility of observer interpretation e.

Towards complete and accurate reporting of studies of diagnostic accuracy: An updated list of essential items for reporting diagnostic accuracy studies. Reporting of precision of estimates for diagnostic accuracy: Receiver-operating characteristic ROC plots: Note that in Figs. The correct dual labeling of the x-axis solves the problem of whether to plot specificity or 1 - specificity on the x-axis.

On the use and computation of likelihood ratios in Clinical Chemistry. Crit Rev Clin Lab Sci ;9: Analysis of serial measurements in medical research. Br Med J ; Recommended nomenclature should be used, including: The most common errors in performing and reporting qPCR data include: Not enough information for others to replicate the experiment, including how the nucleic acid was prepared, reverse transcribed, and amplified.

Landless systems rely upon feed from outside the farm, representing the de-linking of crop and livestock production found more prevalently in Organisation for Economic Co-operation and Development member countries. Synthetic fertilizers are more heavily relied upon for crop production and manure utilization becomes a challenge as well as a source for pollution. Much of this growth is happening in developing countries in Asia, with much smaller amounts of growth in Africa.

Tillage is the practice of breaking up the soil with tools such as the plow or harrow to prepare for planting, for nutrient incorporation, or for pest control. Tillage varies in intensity from conventional to no-till. It may improve productivity by warming the soil, incorporating fertilizer and controlling weeds, but also renders soil more prone to erosion, triggers the decomposition of organic matter releasing CO 2 , and reduces the abundance and diversity of soil organisms.

Pest control includes the management of weeds, insects , mites , and diseases. Chemical pesticides , biological biocontrol , mechanical tillage , and cultural practices are used. Cultural practices include crop rotation, culling , cover crops , intercropping, composting , avoidance, and resistance. Integrated pest management attempts to use all of these methods to keep pest populations below the number which would cause economic loss, and recommends pesticides as a last resort.

Nutrient management includes both the source of nutrient inputs for crop and livestock production, and the method of utilization of manure produced by livestock. Nutrient inputs can be chemical inorganic fertilizers, manure, green manure , compost and minerals.

Manure is used either by holding livestock where the feed crop is growing, such as in managed intensive rotational grazing, or by spreading either dry or liquid formulations of manure on cropland or pastures.

Water management is needed where rainfall is insufficient or variable, which occurs to some degree in most regions of the world. In other areas such as the Great Plains in the U. Payment for ecosystem services is a method of providing additional incentives to encourage farmers to conserve some aspects of the environment.

Measures might include paying for reforestation upstream of a city, to improve the supply of fresh water. Crop alteration has been practiced by humankind for thousands of years, since the beginning of civilization. Altering crops through breeding practices changes the genetic make-up of a plant to develop crops with more beneficial characteristics for humans, for example, larger fruits or seeds, drought-tolerance, or resistance to pests.

Significant advances in plant breeding ensued after the work of geneticist Gregor Mendel. His work on dominant and recessive alleles , although initially largely ignored for almost 50 years, gave plant breeders a better understanding of genetics and breeding techniques. Crop breeding includes techniques such as plant selection with desirable traits, self-pollination and cross-pollination , and molecular techniques that genetically modify the organism.

Domestication of plants has, over the centuries increased yield, improved disease resistance and drought tolerance , eased harvest and improved the taste and nutritional value of crop plants. Careful selection and breeding have had enormous effects on the characteristics of crop plants. Plant selection and breeding in the s and s improved pasture grasses and clover in New Zealand. Extensive X-ray and ultraviolet induced mutagenesis efforts i. The Green Revolution popularized the use of conventional hybridization to sharply increase yield by creating "high-yielding varieties".

For example, average yields of corn maize in the US have increased from around 2. Variations in yields are due mainly to variation in climate, genetics, and the level of intensive farming techniques use of fertilizers, chemical pest control, growth control to avoid lodging. Genetically modified organisms GMO are organisms whose genetic material has been altered by genetic engineering techniques generally known as recombinant DNA technology.

Genetic engineering has expanded the genes available to breeders to utilize in creating desired germlines for new crops. Increased durability, nutritional content, insect and virus resistance and herbicide tolerance are a few of the attributes bred into crops through genetic engineering. Numerous countries have placed restrictions on the production, import or use of GMO foods and crops. Herbicide-resistant seed has a gene implanted into its genome that allows the plants to tolerate exposure to herbicides, including glyphosate.

These seeds allow the farmer to grow a crop that can be sprayed with herbicides to control weeds without harming the resistant crop. Herbicide-tolerant crops are used by farmers worldwide.

In some areas glyphosate resistant weeds have developed, causing farmers to switch to other herbicides. Other GMO crops used by growers include insect-resistant crops, which have a gene from the soil bacterium Bacillus thuringiensis Bt , which produces a toxin specific to insects. These crops resist damage by insects. In some cases, wild species are the primary source of resistance traits; some tomato cultivars that have gained resistance to at least 19 diseases did so through crossing with wild populations of tomatoes.

Agriculture imposes multiple external costs upon society through effects such as pesticide damage to nature especially herbicides and insecticides , nutrient runoff, excessive water usage, and loss of natural environment. Neither included subsidies in their analysis, but they noted that subsidies also influence the cost of agriculture to society.

Agriculture seeks to increase yield and to reduce costs. Yield increases with inputs such as fertilisers and removal of pathogens, predators, and competitors such as weeds. Costs decrease with increasing scale of farm units, such as making fields larger; this means removing hedges , ditches and other areas of habitat.

Pesticides kill insects, plants and fungi. These and other measures have cut biodiversity to very low levels on intensively farmed land. In , the International Resource Panel of the United Nations Environment Programme assessed the environmental impacts of consumption and production. It found that agriculture and food consumption are two of the most important drivers of environmental pressures, particularly habitat change, climate change, water use and toxic emissions.

Agriculture is the main source of toxins released into the environment, including insecticides, especially those used on cotton. This includes GHGs emitted by the use of inorganic fertilisers agro-chemical pesticides and herbicides; GHG emissions resulting from production of these inputs are included in industrial emissions ; and fossil fuel-energy inputs.

A senior UN official and co-author of a UN report detailing this problem, Henning Steinfeld, said "Livestock are one of the most significant contributors to today's most serious environmental problems".

By comparison, all transportation emits Furthermore, the UNEP states that " methane emissions from global livestock are projected to increase by 60 per cent by under current practices and consumption patterns. Land transformation, the use of land to yield goods and services, is the most substantial way humans alter the Earth's ecosystems, and is considered the driving force in the loss of biodiversity. Degradation can be deforestation, desertification , soil erosion , mineral depletion, or chemical degradation acidification and salinization.

Eutrophication , excessive nutrients in aquatic ecosystems resulting in algal blooms and anoxia , leads to fish kills , loss of biodiversity, and renders water unfit for drinking and other industrial uses. Excessive fertilization and manure application to cropland, as well as high livestock stocking densities cause nutrient mainly nitrogen and phosphorus runoff and leaching from agricultural land.

These nutrients are major nonpoint pollutants contributing to eutrophication of aquatic ecosystems and pollution of groundwater, with harmful effects on human populations. It is long known that aquifers in areas as diverse as northern China, the Upper Ganges and the western US are being depleted, and new research extends these problems to aquifers in Iran, Mexico and Saudi Arabia.

Pesticide use has increased since to 2. An alternative argument is that the way to "save the environment" and prevent famine is by using pesticides and intensive high yield farming, a view exemplified by a quote heading the Center for Global Food Issues website: Global warming and agriculture are interrelated on a global scale.

Global warming affects agriculture through changes in average temperatures , rainfall , and weather extremes like storms and heat waves ; changes in pests and diseases; changes in atmospheric carbon dioxide and ground-level ozone concentrations; changes in the nutritional quality of some foods; [] and changes in sea level.

Animal husbandry is also responsible for greenhouse gas production of CO 2 and a percentage of the world's methane, and future land infertility, and the displacement of wildlife.

Agriculture contributes to climate change by anthropogenic emissions of greenhouse gases, and by the conversion of non-agricultural land such as forest for agricultural use.

Current farming methods have resulted in over-stretched water resources, high levels of erosion and reduced soil fertility. There is not enough water to continue farming using current practices; therefore how critical water, land, and ecosystem resources are used to boost crop yields must be reconsidered. A solution would be to give value to ecosystems, recognizing environmental and livelihood tradeoffs, and balancing the rights of a variety of users and interests.

Technological advancements help provide farmers with tools and resources to make farming more sustainable. Since the s, agricultural productivity has increased dramatically, due largely to the increased use of energy-intensive mechanization, fertilizers and pesticides.

The vast majority of this energy input comes from fossil fuel sources. Heavy reliance on petrochemicals has raised concerns that oil shortages could increase costs and reduce agricultural output.

Industrialized agriculture depends on fossil fuels in two fundamental ways: Direct consumption includes the use of lubricants and fuels to operate farm vehicles and machinery. Indirect consumption includes the manufacture of fertilizers, pesticides, and farm machinery. Direct and indirect energy consumption by U. Agriculture accounts for less than one-fifth of food system energy use in the US.

Agricultural economics refers to economics as it relates to the "production, distribution and consumption of [agricultural] goods and services". This is related to the greater efficiency of farming, combined with the increased level of value addition e.

Market concentration has increased in the sector as well, and although the total effect of the increased market concentration is likely increased efficiency, the changes redistribute economic surplus from producers farmers and consumers, and may have negative implications for rural communities.

National government policies can significantly change the economic marketplace for agricultural products, in the form of taxation, subsidies , tariffs and other measures. In the s, non-subsidized farmers in developing countries experienced adverse effects from national policies that created artificially low global prices for farm products.

Between the mids and the early s, several international agreements limited agricultural tariffs, subsidies and other trade restrictions. However, as of [update] , there was still a significant amount of policy-driven distortion in global agricultural product prices. The three agricultural products with the greatest amount of trade distortion were sugar, milk and rice, mainly due to taxation. Among the oilseeds , sesame had the greatest amount of taxation, but overall, feed grains and oilseeds had much lower levels of taxation than livestock products.

Since the s, policy-driven distortions have seen a greater decrease among livestock products than crops during the worldwide reforms in agricultural policy. Commodities are generally reported by production quantities, such as volume, number or weight.

Agricultural science is a broad multidisciplinary field of biology that encompasses the parts of exact, natural, economic and social sciences used in the practice and understanding of agriculture. It covers topics such as agronomy, plant breeding and genetics, plant pathology , crop modelling, soil science, entomology , production techniques and improvement, study of pests and their management, and study of adverse environmental effects such as soil degradation, waste management , and bioremediation.

The scientific study of agriculture began in the 18th century, when Johann Friedrich Mayer conducted experiments on the use of gypsum hydrated calcium sulphate as a fertilizer. Agricultural policy is the set of government decisions and actions relating to domestic agriculture and imports of foreign agricultural products.

Governments usually implement agricultural policies with the goal of achieving a specific outcome in the domestic agricultural product markets. Some overarching themes include risk management and adjustment including policies related to climate change, food safety and natural disasters , economic stability including policies related to taxes , natural resources and environmental sustainability especially water policy , research and development, and market access for domestic commodities including relations with global organizations and agreements with other countries.

Policy programs can range from financial programs, such as subsidies, to encouraging producers to enroll in voluntary quality assurance programs. There are many influences on the creation of agricultural policy, including consumers, agribusiness, trade lobbies and other groups. Agribusiness interests hold a large amount of influence over policy making, in the form of lobbying and campaign contributions. Political action groups, including those interested in environmental issues and labor unions , also provide influence, as do lobbying organizations representing individual agricultural commodities.

Samuel Jutzi, director of FAO's animal production and health division, states that lobbying by large corporations has stopped reforms that would improve human health and the environment. For example, proposals in for a voluntary code of conduct for the livestock industry that would have provided incentives for improving standards for health, and environmental regulations, such as the number of animals an area of land can support without long-term damage, were successfully defeated due to large food company pressure.

From Wikipedia, the free encyclopedia. This is the latest accepted revision , reviewed on 14 September For other uses, see Farming disambiguation. Government ministries Universities and colleges. Agriculture by country companies Biotechnology Livestock Meat industry Poultry farming. Agricultural safety and health. List of countries by GDP sector composition. List of most important agricultural crops worldwide. Countries by agricultural output in billions in USD.

Countries by agricultural output in millions in constant USD and exchange rates. Livestock and Animal husbandry.

List of domesticated animals. Tillage , Crop rotation , and Irrigation. Genetically modified food , Genetically modified crops , Regulation of the release of genetic modified organisms , and Genetically modified food controversies.

Environmental issues with agriculture. Environmental impact of irrigation. Environmental impact of pesticides. Climate change and agriculture. List of sustainable agriculture topics.

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